General information

Coversyl contains a potent ingredient called perindopril arginine. It belongs to the class of angiotensin converting enzyme (ACE) inhibitors. This medication is taken alone or it can be combined with thiazide diuretics that help the body to get rid of excess water. Coversyl improves the flow of blood through the circulatory system. It is the first line medication used in the treatment of high blood pressure and congestive heart failure. It also can be applied to treat diabetic nephropathy, renal disease, systemic sclerosis, coronary artery disease, left ventricular hypertrophy. It works via preventing an angiotensin I from converting into a more potent form that increases salt and water retention in your body.

Directions

You need to consult a doctor regarding the appropriate dosage intake. Do not give up taking the medicine unless it is permitted by your doctor. Usually the standard dose is 4 mg taken daily as a single dose or divided into two smaller portions. The dosage can be increased until your blood pressure is under control. The maximum tolerated dosage is 16 milligrams per day.

Precautions

Before taking you must immediately consult your doctor if you are pregnant, plan to be pregnant as it may cause severe harm to the unborn child. To make sure you can safely take Coversyl you must also inform your doctor if you have cardiac insufficiency, suffered from strokes, liver/kidney diseases, asthma, glaucoma, low or high level of potassium, lupus, gout, diabetes, scleroderma. Follow your doctor's instructions about the type and amount of liquids you should drink.

Contraindications

This medication is contraindicated in patients that are pregnant or breastfeeding or in case the anamnesis includes hypersensitivity to Coversyl or any other ACE inhibitors such as captopril and lisinopril; a history of allergic reactions such as swelling of the face/lips/tongue/throat; lupus, scleroderma; kidney or liver diseases; dehydration; mineral disbalance that involves high potassium or low sodium levels in the blood.

Possible side effect

In case you suffer from allergy that involves hives, face swelling, breathe diminishing, muscle pain, nausea or emesis, morbidity, urine color changing, high fever, chest pain, palpitations, a feeling of extreme dizziness or fainting you need to immediately notify your health care practitioner. There can be less serious side effects that are transient and may involve headache, dizziness, lightheadedness, weakness, numbness, tingling in the hands, feet, arms, or leg, digestive upsets, itching, rash, hyperhidrosis. If any of these symptoms persist or worsen, notify your doctor promptly.

Drug interactions

Coversyl is able to interact with following medicines: with a class of potassium supplements such as K-Dur, Klor-Con; with salt substitutes that contain potassium; with a group of water pills (diuretics) such as triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor), hydrochlorothiazide (HCTZ, HydroDiuril, others); lithium (Lithobid, Eskalith, others); digoxin (Lanoxin); indomethacin (Indocin); with a class of nonsteroidal anti-inflammatory drugs; medications used to affect the bone marrow; gold injections; heparin; products that may increase your potassium level; pseudoephedrine; trimethoprim-containing medications. In case you are already taking one of these medications, you need to adjust Coversyl dosage schedule with your health care practitioner. Please, check with your doctor or pharmacist a list of other medications and food supplements you are allowed to take consentaneously with this product.

Missed dose

In case you have missed to take a dose of the medicine, take it as soon as you remember. If you are already supposed to take your next dose, do not take the dose you forgot and keep your ordinary dosage schedule. Avoid compensating a missed dose by taking an extra one. If you have missed to take a few doses in succession, you should immediately consult your doctor about follow-up actions.

Overdose

If you suspect you have used too much of this medication, seek emergency medical attention right away. You must do this even if symptoms of discomfort or poisoning haven’t been indicated at once. You may need urgent medical attention. Most regular symptoms of overdose involve dizziness, fainting, lassitude, excessive low blood pressure.

Storage

It is recommended to store this medication away from sources of moisture and heat, and in a safe place, far from reach of children and pets. Store it at room temperature of 15-30 degrees C (59-86 F).

Note

The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes. We are not responsible for any direct, indirect, special or other damage caused by use of this information on the site and also for consequences of self-treatment.