General information

Isordil belongs to the group of medicines called nitrates. It is used to prevent and relieve chest pain (angina pectoris) due to coronary artery disease. It is a potent vasodilating agent aimed to relax smooth muscle and widen blood vessels allowing blood and oxygen flow to the heart; therefore it pumps blood more easily. Isordil lowers peripheral arterial blood pressure, decreases venous return and left ventricular filling pressure.

Directions

You need to consult a doctor regarding the appropriate dosage intake. Do not give up taking the medicine unless it is permitted by your doctor. Administer the intake orally with a full glass of water. It is desirable to take it on an empty stomach 30 minutes before or 2 hours after food. This medication is not chewed, crushed or broken while taking. Generally the standard recommended dosage is 5 mg to 20 mg taken two or three times per day. Some patients may require a dosage adjustment depending on the disease and healthy conditions.

Precautions

This product may contain inactive ingredients, which can cause allergic reactions. This medication is prescribed cautiously if you anamnesis contains a history of heart attacks or heart failure, allergic reactions to isosorbide dinitrate and nitrates. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

Contraindications

ISORDIL is contraindicated in patients suffering from severe anaemia, recent head trauma, cerebral haemorrhage, severe renal or hepatic failure; or in patients with increased intracranial pressure. Consult your doctor before taking, in case you are pregnant, plan to be pregnant or breastfeeding as there is no report if this medicine can cause any harm to an unborn baby, or excrete into the breast milk.

Possible side effect

You have to immediately notify your health care professional if you suffer from any bothersome symptoms such as throbbing headache, warmness and skin flushing, dizziness, lightheadedness, blurred vision, dryness of mouth, skin rash, urticaria, itching, blue-colored lips, worsening angina pain, fingernails, or palms, fainting, difficulty breathing, palpitations, high fever, and convulsions. This is not a complete list of all possible side effects. Others may occur in some patients and there may be some side effects not known yet. In case you have experienced any side effects not listed above, immediately seek emergency medical attention.

Drug interactions

You must notify your health care practitioner if you are already taking a group of medicines used to treat erectile dysfunction such as sildenafil (Viagra), tadalafil (Cialis) or vardenafil (Levitra Soft). Amplification of vasodilatation caused by interaction between nitrate and sildenafil can lead to excessive low blood pressure. Inform your doctor if you apply any other medication used to treat angina pectoris or cardiac insufficiency. In case you are not confident whether this medicinal product is compatible with other medicines or supplements, discuss it with your doctor or pharmacist.

Missed dose

In case you have missed to take a dose of this medicinal product, take it as soon as possible. If you are already supposed to take your next dose, do not take the dose you forgot and keep your ordinary dosage schedule. Do not take two dosages right away.

Overdose

If you think you overdosed the medicine, immediately contact your local poison center and notify your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

Storage

Store this product in a dry tight container away from sunlight, heat and moisture at room temperature between 25 degrees C (77 F). Do not store it in the bathroom. Keep this product out of the reach of children and pets. Do not apply any remnants of the medication after the expiry date.

Note

The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes. We are not responsible for any direct, indirect, special or other damage caused by use of this information on the site and also for consequences of self-treatment.